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{{cat}}
 
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Also known as ''lymphocytic-plasmacytic cholangitis or cholangiohepatitis'', ''lymphocytic portal hepatitis'' and ''non-suppurative cholangitis or cholangiohepatitis''.
 
Also known as ''lymphocytic-plasmacytic cholangitis or cholangiohepatitis'', ''lymphocytic portal hepatitis'' and ''non-suppurative cholangitis or cholangiohepatitis''.
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==Signalment==
 
==Signalment==
 
*Young to middle-aged cats, 50% under 4 years old.
 
*Young to middle-aged cats, 50% under 4 years old.
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==Description==
 
==Description==
 
'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - WikiBlood|lymphocytes]] and [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]].  Bile duct hypertrophy and [[Liver General Pathology - Pathology#Fibrosis - Repair|fibrosis]] are present.  However, lymphocytic cholangitis does not progress to biliary [[Liver General Pathology - Pathology#Cirrhosis|cirrhosis]].  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with [[Pancreatitis - WikiClinical|pancreatitis]], compared to [[Neutrophilic Cholangitis]]
 
'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - WikiBlood|lymphocytes]] and [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]].  Bile duct hypertrophy and [[Liver General Pathology - Pathology#Fibrosis - Repair|fibrosis]] are present.  However, lymphocytic cholangitis does not progress to biliary [[Liver General Pathology - Pathology#Cirrhosis|cirrhosis]].  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with [[Pancreatitis - WikiClinical|pancreatitis]], compared to [[Neutrophilic Cholangitis]]
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==Diagnosis==
 
==Diagnosis==
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*Antioxidants such as S-adenosylmethionine and vitamin E.
 
*Antioxidants such as S-adenosylmethionine and vitamin E.
 
**These are used to counteract the potent oxidising property of bile.
 
**These are used to counteract the potent oxidising property of bile.
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==Prognosis==
 
==Prognosis==
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