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===Laboratory Tests===
===Laboratory Tests===
Serum Biochemistry
Serum Biochemistry
Hypercalcaemia is present in 50%-90% of dogs with anal sac adenocarcinoma. This is thought to occur due to the expression of a gene for parathyroid hormone-related peptide (PTH-rP)by the tumour which has actions similar to parathyroid hormone.
Hypercalcaemia is present in 50%-90% of dogs with anal sac adenocarcinoma. This is thought to occur due to the expression of a gene for parathyroid hormone-related peptide(PTH-rP)by the tumour. Parathyroid hormone-related peptide(PTH-rP)has actions similar to parathyroid hormone where it acts to increase calcium levels in the blood. . In severe cases of hypercalcaemia organ function can become impaired
*Phosphate
*Phosphate
*Renal function
*Renal function
Urinalysis
Patients may be dehydrated with a pre-renal azotaemia due but have a relatively low [[Urine Analysis - Pathology |urine specific gravity]].
===Radiography===
===Radiography===