Changes

==Fibrinous/Diptheritic Inflammation==

==Fibrinous/Diptheritic Inflammation==

*Severe damage to epithelium produces exudation of fibrin - with formation of dry white fibrinous deposit - diptheritic membrane.

*Severe damage to epithelium produces exudation of fibrin - with formation of dry white fibrinous deposit - diptheritic membrane.

*Usually associated with organism [[fusobacterium necrophorum]] found everywhere in environment (but strict anaerobe).

*Usually associated with organism ''[[Fusobacterium necrophorum]]'' found everywhere in environment (but strict anaerobe).

*Produces lesions that damage epithelium due to toxin that damages vessels.

*Produces lesions that damage epithelium due to toxin that damages vessels.

*Often a secondary invader but can be a primary pathogen.

*Often a secondary invader but can be a primary pathogen.

*Synonyms: '''laryngeal diphtheria, calf diphtheria'''

*Synonyms: '''laryngeal diphtheria, calf diphtheria'''

*Common disease in cattle, and can occur in swine

*Common disease in cattle, and can occur in swine

*Caused by infection with [[Fusobacterium|''Fusobacterium necrophorum'']]   

*Caused by infection with [[Fusobacterium necrophorum|''Fusobacterium necrophorum'']]   

*Lesions may also be found in other parts of the [[Nasopharynx Inflammatory - Pathology#Infectious causes of pharyngitis|oropharynx]]   

*Lesions may also be found in other parts of the [[Nasopharynx Inflammatory - Pathology#Infectious causes of pharyngitis|oropharynx]]   

*The bacterium usually gains entry through damaged mucosal surfaces e.g. after viral infections or injury following (poor!) use of dosing guns, coarse poor quality roughage

*The bacterium usually gains entry through damaged mucosal surfaces e.g. after viral infections or injury following (poor!) use of dosing guns, coarse poor quality roughage