Difference between revisions of "Testicular Feminisation"

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(Redirected page to Intersex#Testicular feminisation)
 
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== Aetiology ==
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#redirect[[Intersex#Testicular feminisation]]
 
 
 
 
* Genotype XY as should be in the male.
 
* Testes develop normally and secrete Androgens and MIH
 
* Foetal genetalia are genetically insensitive to the actions of Androgens due to a point mutation in the Androgen receptor.
 
 
 
== Consequence ==
 
 
 
* Wolffian Ducts regress, allowing formation of '''female external genetalia''':
 
** Labia
 
** Clitoris
 
** Vagina
 
* Sertoli cells are present and continue to secrete MIH, causing Mullarian Duct regression.
 
* Since both Wolffian AND Mullarian Ducts regress, there is '''no internal genetalia'''.
 
 
 
 
 
 
 
[[Category:Reproductive Disorders]]
 
[[Category:Reproductive Diseases - Dog]]
 
[[Category:Reproductive Diseases - Cat]]
 

Latest revision as of 23:06, 26 October 2011