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| − | ===Myasthenia gravis (MG)=== | + | ===[[Myasthenia Gravis]] (MG)=== |
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| − | *'''Acquired'''
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| − | **Autoimmune disease
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| − | ***Antibodies directed against acetyl choline receptors
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| − | **Associated with [[Thymus neoplasia|thymomas]], [[Megaoesophagus|megaoesophagus]] and dysphagia
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| − | **In adult dogs
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| − | *'''Congenital'''
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| − | **Inherited deficiency in acetyl choline receptors
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| − | **Rare
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| − | **Newfoundland, Jack Russel Terrier, Springer Spaniels – genetic predisposition
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| − | **In dogs – 4 DLA genes recognized: DLA-12, DLA-88, DLA-79 and DLA-64
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| − | **Associated with HLA gene in humans
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| − | **No antibodies against acetyl choline receptors in serum
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| − | **Non-specific muscle [[Muscles Degenerative - Pathology#Atrophy|disuse atrophy]] and fibrosis or no changes on histology
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| − | *Both forms manifest as weakness which worsens on exercise
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| − |
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| − | [[Category:Muscles - Developmental Pathology]]
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