Difference between revisions of "Inclusion Body Rhinitis"
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[[Infectious_Causes_of_Inflammation_Flashcards_-_Pathology|Infectious Causes of Inflammation Pathology Flashcards]] | [[Infectious_Causes_of_Inflammation_Flashcards_-_Pathology|Infectious Causes of Inflammation Pathology Flashcards]] | ||
| − | [[Category:Herpesviridae]][[Category:Pig Viruses]][[Category:To_Do_- | + | [[Category:Herpesviridae]][[Category:Pig Viruses]][[Category:To_Do_-_CABI]] |
[[Category:Respiratory_Viral_Infections]][[Category:Respiratory Diseases - Pig]] | [[Category:Respiratory_Viral_Infections]][[Category:Respiratory Diseases - Pig]] | ||
Revision as of 14:38, 11 June 2011
Inclusion body rhinitis
- Herpesviridae, porcine cytomegalovirus
- Disease of suckling piglets 1-5 wks of age
- Clinical signs: those associated with acute/subacute rhinitis (ie: serous nasal discharge, progressing to catarrhal or purulent discharge with time and secondary bacterial infections; sneezing; pyrexia), fever in young piglets (3-8wks old)
- May progress to sinusitis, otitis media or pneumonia
- Morbitity high, mortality low
- Gross pathology - catarrhal discharge becoming purulent (secondary infection)
- Histology:
- Large basophilic intranuclear inclusion bodies in the surface and subepithelium of nasal and sinus glandular epithelium with lymphocytic infiltration of the mucosa
- Bursting of nucleus with cell necrosis and sloughing of necrotic epithelium
- Can develop viraemic stage, with inclusions and focal necrotising lesions in other organs eg: renal tubular epithelium
- Usually younger piglets, can die during this phase
- Usually resolves if uncomplicated but rhinitis may persist if secondary infection is present
- May persist in pulmonary macrophages