Difference between revisions of "Transgenic Animals - Anatomy & Physiology"
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* Many mouse transgenics have been created to serve as models for human genetic diseases. | * Many mouse transgenics have been created to serve as models for human genetic diseases. | ||
| − | * Less successful in other species, but goats have been created that secrete human factor VIII in their milk. | + | * Less successful in other species, but goats have been created that secrete human [[General_Pathology_-_Haemostasis#Factor_VIII|factor VIII]] in their milk. |
** Cheap treatment for [[General_Pathology_-_Haemostasis#Diseases_associated_with_coagulation_factor_defects|bleeding disorders]] with little risk of disease transfer. | ** Cheap treatment for [[General_Pathology_-_Haemostasis#Diseases_associated_with_coagulation_factor_defects|bleeding disorders]] with little risk of disease transfer. | ||
* Area of much future development. | * Area of much future development. | ||
* Injection of specific gene constructs into the newly fertilized [[The_Ovary_-_Oocytes_-_Anatomy_%26_Physiology|oocyte]], so that they become part of the dividing cell. Thus they are encorporated and expressed in the individual. | * Injection of specific gene constructs into the newly fertilized [[The_Ovary_-_Oocytes_-_Anatomy_%26_Physiology|oocyte]], so that they become part of the dividing cell. Thus they are encorporated and expressed in the individual. | ||
* Constructs may be from the same or different species as the [[The_Ovary_-_Oocytes_-_Anatomy_%26_Physiology|oocyte]]. | * Constructs may be from the same or different species as the [[The_Ovary_-_Oocytes_-_Anatomy_%26_Physiology|oocyte]]. | ||
Revision as of 11:10, 17 July 2008
- Many mouse transgenics have been created to serve as models for human genetic diseases.
- Less successful in other species, but goats have been created that secrete human factor VIII in their milk.
- Cheap treatment for bleeding disorders with little risk of disease transfer.
- Area of much future development.
- Injection of specific gene constructs into the newly fertilized oocyte, so that they become part of the dividing cell. Thus they are encorporated and expressed in the individual.
- Constructs may be from the same or different species as the oocyte.