Difference between revisions of "EPI"
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<big><center>[[Pancreas Developmental - Pathology|'''BACK TO PANCREAS - DEVELOPMENTAL''']]</center></big> | <big><center>[[Pancreas Developmental - Pathology|'''BACK TO PANCREAS - DEVELOPMENTAL''']]</center></big> | ||
<big><center>[[Pancreas - degenerative|'''BACK TO PANCREAS - DEGENERATIVE''']]</center></big> | <big><center>[[Pancreas - degenerative|'''BACK TO PANCREAS - DEGENERATIVE''']]</center></big> | ||
| − | <big><center>[[Pancreas - | + | <big><center>[[Pancreas Inflammatory - Pathology|'''BACK TO PANCREAS - INFLAMMATORY''']]</center></big> |
<big><center>[[Pancreas - hyperplastic and neoplastic|'''BACK TO PANCREAS - HYPERPLASTIC AND NEOPLASTIC''']]</center></big> | <big><center>[[Pancreas - hyperplastic and neoplastic|'''BACK TO PANCREAS - HYPERPLASTIC AND NEOPLASTIC''']]</center></big> | ||
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*Leading to insufficient activity of digestive enzymes in the lumen of the small intestine | *Leading to insufficient activity of digestive enzymes in the lumen of the small intestine | ||
*Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI | *Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI | ||
| − | *Most common in dog - usually associated with [[Pancreas - degenerative|pancreatic atrophy]] or [[Pancreas - | + | *Most common in dog - usually associated with [[Pancreas - degenerative|pancreatic atrophy]] or [[Pancreas Inflammatory - Pathology#Chronic Pancreatitis|chronic pancreatitis]] |
*Occurs occasionally in other species, esp. calves with [[Pancreas Developmental - Pathology#Pancreatic hypoplasia|pancreatic hypoplasia]] and in cats | *Occurs occasionally in other species, esp. calves with [[Pancreas Developmental - Pathology#Pancreatic hypoplasia|pancreatic hypoplasia]] and in cats | ||
*'''Clinical signs''' | *'''Clinical signs''' | ||
Revision as of 14:49, 20 August 2008
- Exocrine pancreatic insufficiency (EPI) is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas
- Leading to insufficient activity of digestive enzymes in the lumen of the small intestine
- Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI
- Most common in dog - usually associated with pancreatic atrophy or chronic pancreatitis
- Occurs occasionally in other species, esp. calves with pancreatic hypoplasia and in cats
- Clinical signs
- Steatorrhoea
- Diarrhoea
- Weight loss
- Increased appetite
- In contrast, horses with very little pancreatic tissue develop hypoinsulinism but rarely EPI