Difference between revisions of "Vaccines"
Jump to navigation
Jump to search
| Line 3: | Line 3: | ||
---- | ---- | ||
| + | ==Why Vaccinate?== | ||
| − | === | + | *To protect against infectious diseases |
| + | |||
| + | *Where there is no effective treatment once infected | ||
| + | **E.g. FeLV, FIV | ||
| + | |||
| + | *Where disease is life-threatening | ||
| + | **E.g. Canine Parvovirus | ||
| + | |||
| + | *To prevent the spread of disease | ||
| + | **E.g. Rabies, FMDV | ||
| + | |||
| + | ==How do we vaccinate?== | ||
| + | |||
| + | *Usually by subcutaneous injection for '''systemic''' protection (IgG) | ||
| + | |||
| + | *For '''mucosal''' immune reponse, intranasal administration is best (IgA) | ||
| + | |||
| + | ==What do we vaccinate with?== | ||
| + | |||
| + | '''Passive immunisation''' | ||
| + | *Administer antibodies | ||
| + | **Maternally-derived antibodies in colostrum | ||
| + | **Antiserum (artificial) | ||
| + | |||
| + | *Immediate protection | ||
| + | |||
| + | *Short duration of action | ||
| + | |||
| + | '''Active immunisation''' | ||
| + | *Administer antigen so the patient's own antibodies protect against disease | ||
| + | **Living organisms | ||
| + | **Dead organisms | ||
| + | **Toxoids | ||
| + | **Subunit antigens | ||
| + | **DNA | ||
| + | |||
| + | *Delay in protection | ||
| + | |||
| + | *Often needs two or more doses | ||
| + | |||
| + | *Long duration of action | ||
| + | |||
| + | ==What antigens do we use in the vaccine?== | ||
| + | |||
| + | ==Links== | ||
| + | |||
| + | ==Creators== | ||
| + | |||
| + | [[Natalie Brown]] | ||
Revision as of 16:01, 25 August 2008
Why Vaccinate?
- To protect against infectious diseases
- Where there is no effective treatment once infected
- E.g. FeLV, FIV
- Where disease is life-threatening
- E.g. Canine Parvovirus
- To prevent the spread of disease
- E.g. Rabies, FMDV
How do we vaccinate?
- Usually by subcutaneous injection for systemic protection (IgG)
- For mucosal immune reponse, intranasal administration is best (IgA)
What do we vaccinate with?
Passive immunisation
- Administer antibodies
- Maternally-derived antibodies in colostrum
- Antiserum (artificial)
- Immediate protection
- Short duration of action
Active immunisation
- Administer antigen so the patient's own antibodies protect against disease
- Living organisms
- Dead organisms
- Toxoids
- Subunit antigens
- DNA
- Delay in protection
- Often needs two or more doses
- Long duration of action