Difference between revisions of "Vaccines"

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*Short duration of action
 
*Short duration of action
  
 +
[[Image:Active Immunisation.jpg|thumb|right|150px|Active Immunisation - Copyright nabrown RVC]]
 
'''Active immunisation'''
 
'''Active immunisation'''
[[Image:Active Immunisation.jpg|thumb|right|150px|Active Immunisation - Copyright nabrown RVC]]
 
 
*Administer antigen so the patient's own antibodies protect against disease
 
*Administer antigen so the patient's own antibodies protect against disease
 
**Living organisms
 
**Living organisms

Revision as of 16:13, 25 August 2008

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Why Vaccinate?

  • To protect against infectious diseases
  • Where there is no effective treatment once infected
    • E.g. FeLV, FIV
  • Where disease is life-threatening
    • E.g. Canine Parvovirus
  • To prevent the spread of disease
    • E.g. Rabies, FMDV

How do we vaccinate?

  • Usually by subcutaneous injection for systemic protection (IgG)
  • For mucosal immune reponse, intranasal administration is best (IgA)

What do we vaccinate with?

Passive Immunisation - Copyright nabrown RVC

Passive immunisation

  • Administer antibodies
    • Maternally-derived antibodies in colostrum
    • Antiserum (artificial)
  • Immediate protection
  • Short duration of action
Active Immunisation - Copyright nabrown RVC

Active immunisation

  • Administer antigen so the patient's own antibodies protect against disease
    • Living organisms
    • Dead organisms
    • Toxoids
    • Subunit antigens
    • DNA
  • Delay in protection
  • Often needs two or more doses
  • Long duration of action

What antigens do we use in the vaccine?

Links

Creators

Natalie Brown

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