Difference between revisions of "Testicular Feminisation"
Jump to navigation
Jump to search
m |
|||
| Line 4: | Line 4: | ||
|linktext =Reproductive System | |linktext =Reproductive System | ||
|maplink = Reproductive System (Content Map) - Anatomy & Physiology | |maplink = Reproductive System (Content Map) - Anatomy & Physiology | ||
| − | |||
|sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development | |sublink1=Reproductive System - Anatomy & Physiology#Fertilisation.2C Implantation and Early Embryonic Development | ||
|subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT | |subtext1=FERTILISATION , IMPLANTATION AND EARLY EMBRYONIC DEVELOPMENT | ||
| Line 26: | Line 25: | ||
* Sertoli cells are present and continue to secrete MIH, causing Mullarian Duct regression. | * Sertoli cells are present and continue to secrete MIH, causing Mullarian Duct regression. | ||
* Since both Wolffian AND Mullarian Ducts regress, there is '''no internal genetalia'''. | * Since both Wolffian AND Mullarian Ducts regress, there is '''no internal genetalia'''. | ||
| + | |||
| + | |||
| + | |||
| + | [[Category:Reproductive System]] | ||
Revision as of 15:10, 22 August 2010
|
|
Aetiology
- Genotype XY as should be in the male.
- Testes develop normally and secrete Androgens and MIH
- Foetal genetalia are genetically insensitive to the actions of Androgens due to a point mutation in the Androgen receptor.
Consequence
- Wolffian Ducts regress, allowing formation of female external genetalia:
- Labia
- Clitoris
- Vagina
- Sertoli cells are present and continue to secrete MIH, causing Mullarian Duct regression.
- Since both Wolffian AND Mullarian Ducts regress, there is no internal genetalia.