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Pressure on neighbouring structures causes clinical signs, for example:
 
Pressure on neighbouring structures causes clinical signs, for example:
 
*Pressure on the optic chiasma produces ocular signs.
 
*Pressure on the optic chiasma produces ocular signs.
*Pressure on the hypothalamus may lead to [[Frohlich's adiposogenital syndrome]].
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*Pressure on the hypothalamus may lead to [[Frohlich's Adiposogenital Syndrome - Pathology|Frohlich's adiposogenital syndrome]].
 
*Pressure on the neurohyposphysis may lead to failure of ADH secretion.  This will allow large volumes of water to be lost form the kidney; [[diabetes insipidus]].
 
*Pressure on the neurohyposphysis may lead to failure of ADH secretion.  This will allow large volumes of water to be lost form the kidney; [[diabetes insipidus]].
 
[[Image:Pituitary tumour.jpg|right|thumb|125px|<small><center>'''Pituitary neoplasia'''. Courtesy of A. Jefferies</center></small>]]
 
[[Image:Pituitary tumour.jpg|right|thumb|125px|<small><center>'''Pituitary neoplasia'''. Courtesy of A. Jefferies</center></small>]]