Difference between revisions of "Herpesviridae"
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* Bovine herpesvirus - 1 (Infectious bovine rhinotracheitis virus) contributes to [[Intestines - Catarrhal Enteritis#Undifferentiated Neonatal Calf Diarrhoea|undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves; and [[Nasal cavity - inflammatory#Rhinitis|rhinitis]] | * Bovine herpesvirus - 1 (Infectious bovine rhinotracheitis virus) contributes to [[Intestines - Catarrhal Enteritis#Undifferentiated Neonatal Calf Diarrhoea|undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves; and [[Nasal cavity - inflammatory#Rhinitis|rhinitis]] | ||
| + | ===Bovine herpesvirus -1=== | ||
| + | *Causes '''Infectious bovine rhinotracheitis (IBR)''' | ||
| + | *Highly infectious URT disease of cattle | ||
| + | *High morbidity, low mortality | ||
| + | *Aerosol transmission - requires close contact between animals | ||
| + | *BHV-1 infects the respiratory mucosal epithelial cells (intranuclear inclusion eosinophilic inclusion bodies)from nasal mucosa down to bronchioles | ||
| + | **leading to neutrophilic inflammation of varying severity.... serous -> catarrhal -> purulent nasal discharge, sneezing, coughing. | ||
| + | **with secondary bacterial infection (eg: Pasturella spp., Mycoplasma spp., Fusobacterium necrophorum) can lead to fibrinous to necrotizing inflammation; mucosal sloughing, ulceration... pyrexia, dyspnoea ... inhalation pneumonia... death. | ||
| + | *Clinical signs include coughing, discharge, lacrimation, and increased respiratory rate. | ||
| + | *Clinical disease most severe in young calves - can develop mucosal ulcerative lesions in the oesophagus and forestomachs and viraemia with multiorgan infection. | ||
| + | *Cause of abortion >5 months of gestation | ||
| + | |||
Revision as of 13:59, 17 August 2007
Introduction
- Bovine herpesvirus - 1 (Infectious bovine rhinotracheitis virus) contributes to undifferentiated neonatal calf diarrhoea, a mixed viral enteritis in calves; and rhinitis
Bovine herpesvirus -1
- Causes Infectious bovine rhinotracheitis (IBR)
- Highly infectious URT disease of cattle
- High morbidity, low mortality
- Aerosol transmission - requires close contact between animals
- BHV-1 infects the respiratory mucosal epithelial cells (intranuclear inclusion eosinophilic inclusion bodies)from nasal mucosa down to bronchioles
- leading to neutrophilic inflammation of varying severity.... serous -> catarrhal -> purulent nasal discharge, sneezing, coughing.
- with secondary bacterial infection (eg: Pasturella spp., Mycoplasma spp., Fusobacterium necrophorum) can lead to fibrinous to necrotizing inflammation; mucosal sloughing, ulceration... pyrexia, dyspnoea ... inhalation pneumonia... death.
- Clinical signs include coughing, discharge, lacrimation, and increased respiratory rate.
- Clinical disease most severe in young calves - can develop mucosal ulcerative lesions in the oesophagus and forestomachs and viraemia with multiorgan infection.
- Cause of abortion >5 months of gestation
- Feline viral rhinotracheitis in rhinitis