Changes

====Fibrinoid Degeneration====

====Fibrinoid Degeneration====

Fibrinoid degeneration

* Fibrinoid degeneration features a material which is fibrin-like.

This implies that there is a

* Is essentially a focal death of cells in the walls of small blood vessels (usually arterioles).  

material which is fibrin-like,

** Parts of the vessel wall become replaced by a granular material.

and is essentially a focal death

*** Pinkish-red (i.e. eosin-staining).

of cells in the walls of small

*** Has some of the appearance and staining properties of fibrin.

blood vessels, usually

*** Consists partly of degenerated muscle and elastic fibres, and partly of an increased amount of protein ground substance around the degenerated fibres.  

arterioles. Parts of the vessel

*** Looks like a red smudge in the vessel wall when viewed histologically.

wall become replaced by a

homogenous or granular

eosin-staining material, which

has some of the appearance

and staining properties of

fibrin. This pinkish-red

material consists partly of

degenerated muscle and elastic

fibres, and partly of an

increased amount of protein ground substance around the degenerated fibres. Its main

the blood vessels. When viewed histologically, the fibrinoid degeneration is like a red

smudge in part of the vessel wall.

====Amyloidosis====

====Amyloidosis====