Chromoblastomycosis

• Occurs in horses, dogs, cats and humans

• Caused by dematiaceous fungi:
  • Exophilia jeanselmeri, Phialophora, Cladosporium carrionii, Fonsecaea pedrosoi

• Enters tissue through wounds or sites of tissue trauma
  • Limited to subcutaneous and cutaneous tissues

• Causes hyperplasia and formation of verrucoid, warty nodules
  • Warts are irregular, vegetative and pedunculated

• Spread is via the lymphatic system
  • Dissemination to other tissues and organs can occur

• Chronic condition which will progress if not treated

• Treatment includes Ketoconazole, 5-fluorocytosine and amphotericin B