Difference between revisions of "Shigella"

Revision as of 11:23, 6 June 2010

Not significant cause of infection in domestic animals
Causes dysentery in humans and primates
Enteroinvasive, invading the intestinal mucosa and causing necrosis
Do not cause systemic disease - they do not invade beyond the lamina propria to the bloodstream
A large plasmid permits survival in cells and is responsible for invasivenss
Closely related to E. coli - some strains produce Shiga toxin which is related to vero cytotoxin of E. coli

Shigella is are enteroinvasive,
- Penetrate the intestinal mucosa.
- Cause necrosis in patches of mucosa.
Shigella do not invade beyond the lamina propria to the bloodstream.
Invasive potential is carried by a large plasmid.
- Relates to the ability to survive inside the host cells.
Some strains produce Shiga toxin.
- Related to vero cytotoxin of some pathogenic strains of E.coli.

@@ Line 5: / Line 5: @@
 *A large plasmid permits survival in cells and is responsible for invasivenss
 *Closely related to [[Escherichia coli|''E. coli'']] - some strains produce Shiga toxin which is related to vero cytotoxin of ''E. coli''
+* Cause of dysentery in humans and primates.
+===Dysentery in Humans and Primates===
+* [[Shigella|''Shigella'']] is are enteroinvasive,
+** Penetrate the intestinal mucosa.
+** Cause necrosis in patches of mucosa.
+* [[Shigella|''Shigella'']] do not invade beyond the lamina propria to the bloodstream.
+* Invasive potential is carried by a large plasmid.
+** Relates to the ability to survive inside the host cells.
+* Some strains produce Shiga toxin.
+** Related to vero cytotoxin of some pathogenic strains of [[Escherichia coli|''E.coli'']].
 [[Category:Enterobacteriaceae]]
+[[Category:Enteritis,_Bacterial]]