Difference between revisions of "Category:Liver - Degenerative Pathology"

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[[Equine Hyperlipidaemia]]
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[[Ovine White Liver Disease]]
  
 
===associated with derangement of carbohydrate metabolism===
 
===associated with derangement of carbohydrate metabolism===

Revision as of 12:58, 7 June 2010


Equine Hyperlipidaemia

Ovine White Liver Disease

associated with derangement of carbohydrate metabolism

Diabetes mellitus

  • where there is insufficient insulin or a decrease in number of insulin receptors in cells
  • seen mostly in dogs
  • produces a markedly fatty liver due to release of fat from the fat stores for use as an energy source

Ketosis

  • due to an excessive drain on carbohydrate stores because pregnant and lactating animals have a continuous demand for glucose
  • ketosis results when fat metabolism which occurs in response to the increased energy demand is excessive
  • ketone bodies accumulate in the blood and there is marked fatty change in the liver
  • can occur in starvation but commonly seen in two conditions in livestock:
ketosis of cattle (acetonemia)
  • occurs in high yielding dairy cows a few weeks postpartum
  • due to excessive loss of glucose in the milk
  • milk yield drops
  • smell of ketones on the breath
  • ketones excreted in the milk
  • self-limiting condition
pregnancy toxaemia in sheep
  • occurs in ewes in late pregnancy carrying twin lambs 'twin lamb disease'
  • drain of carbohydrate stores is due to rapidly growing foetuses
  • serious condition and highly fatal
  • clinical signs (neurological)
    • apparent blindness
    • dullness
    • convulsions
    • coma
  • sequelae
    • foetuses die
    • apparent recovery in ewe until toxaemia from the decomposing foetuses results in the ewe's death


associated with anoxia and toxaemia

anoxia

  • passive congestion
  • anaemias

toxaemia

  • toxins absorbed from the gut interfere with many stages of triglyceride metabolism

Pages in category "Liver - Degenerative Pathology"

The following 9 pages are in this category, out of 9 total.