Difference between revisions of "Hypersensitivity Flashcards"
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*Oedema | *Oedema | ||
*Mucous production | *Mucous production | ||
| − | *Chemoattractants cause the influx of [[Neutrophils|neutrophils]], basophils, [[[[Monocytes | + | *Chemoattractants cause the influx of [[Neutrophils|neutrophils]], basophils, [[[[Monocytes|monocytes]]]] and plasma |
*Vasoactive and inflammatory peptides cause the contraction of smooth muscle fibres | *Vasoactive and inflammatory peptides cause the contraction of smooth muscle fibres | ||
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*Used for testing TB in cattle | *Used for testing TB in cattle | ||
*Injection of intradermal antigen into the skin | *Injection of intradermal antigen into the skin | ||
| − | *A skin reaction (infiltration of lymphocytes and [[[[Monocytes | + | *A skin reaction (infiltration of lymphocytes and [[[[Monocytes|monocytes]]]]) peaking at 48-72 hours indicates prior exposure to the antigen or ongoing infection |
|l7=Type IV Hypersensitivity - WikiBlood#2. Granulomatous | |l7=Type IV Hypersensitivity - WikiBlood#2. Granulomatous | ||
</FlashCard> | </FlashCard> | ||
Revision as of 12:42, 12 June 2010
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Hypersensitivity
| Question | Answer | Article | |
| What is hypersensitivity? |
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Link to Article | |
| Which two scientists proposed the mechanism for distinguishing between the different types of hypersensitivity reactions? | Gell and Coombs
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Link to Article | |
| Complete the following sentences
Types I, II and III hypersensitivity are ??? reactions. Type IV hypersensitivity is a ??? reaction. |
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Link to Article | |
Type I Hypersensitivity
| Question | Answer | Article | |
| What is type I hypersensitivity also known as? |
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Link to Article | |
| What is the name of antigens which cause type I hypersensitivity? | Allergens
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Link to Article | |
| Name some common allergens which cause a type I hypersensitivity reaction |
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Link to Article | |
| Mast cells are caused to degranulate releasing cytokines. What affects do these cytokines have on the infected area? |
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Link to Article | |
| Name some examples of type I hypsensitivity reactions |
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Link to Article | |
Type II Hypersensitivity
| Question | Answer | Article | |
| What types of immunoglobulin are produced in type II hypersensitivity reactions and are they produced against soluble or fixed antigens? |
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Link to Article | |
| What is the main mechanism of type II hypersensitivity reactions? | Neutralisation blockage of receptors
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Link to Article | |
| Which immunological processes does the type II reaction use to destroy target cells? Give examples for each process? |
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Link to Article | |
Type III Hypersensitivity
| Question | Answer | Article | |
| Which immunoglobulin is produced in type III hypersensitivity and is it produced against soluble or fixed antigens? |
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Link to Article | |
| What does inhaling antigen locally lead to? | Hypersensitivity pneumonitis
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Link to Article | |
| What other conditions can be caused by a local type III hypersensitivity response? |
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Link to Article | |
| What general effects does increased levels of systemic antigen have? |
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Link to Article | |
| Give an example of a type III hypersensitivity reaction where the antigen is a self antigen | Systemic lupus erythematous (SLE)
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Link to Article | |
Type IV Hypersensitivity
| Question | Answer | Article | |
| What is type IV hypersensitivity also known as? | Delayed-type hypersensitivity
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Link to Article | |
| What effects do a CD4+ helper cell hypersensitivity response have? |
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Link to Article | |
| What effect does a CD8+ cytotoxic hypersensitivity response have? | Destruction of normal cells
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Link to Article | |
| What are the two types of type IV hypersensitivity reactions? |
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Link to Article | |
| What are the main cells involved in contact dermatitis? | Mononuclear cells
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Link to Article | |
| Give two examples of infections causing a granulomatous response |
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Link to Article | |
| What is the tuberculin test? |
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Link to Article | |