Difference between revisions of "Gastrinoma"

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*Metastases to [[Liver - Anatomy & Physiology|liver]] and local lymph nodes are common
 
*Metastases to [[Liver - Anatomy & Physiology|liver]] and local lymph nodes are common
 
[[Category:Pancreas_-_Hyperplastic_and_Neoplastic_Pathology]][[Category:Endocrine_System_-_Pathology]][[Category:Dog]][[Category:Cat]]
 
[[Category:Pancreas_-_Hyperplastic_and_Neoplastic_Pathology]][[Category:Endocrine_System_-_Pathology]][[Category:Dog]][[Category:Cat]]
[[Category:To_Do_-_Clinical]][[Category:Neoplasia]]
+
[[Category:Neoplasia]]
 +
[[Category:To_Do_-_James]]

Revision as of 17:29, 22 July 2010

Image of pancreatic garstrinoma in a dog from Cornell Veterinary Medicine

  • Described in dogs, cats
  • Known as Zollinger-Ellison syndrome in humans
  • Uncommon compared to beta cell neoplasms
  • Excess gastrin causes hyperacidity in the stomach and mucosal hyperplasia of the antral region causing gastric and duodenal ulceration

Clinical signs

Pathology

  • Multiple variably sized neoplasms
  • Increased connective tissue mass - firm
  • Partiallty encapsulated
  • Invade locally
  • Metastases to liver and local lymph nodes are common