Difference between revisions of "Case 1"
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[[Image:Case pic 3.jpg|left|thumb|125px|<small><center>'''Histology; hypertrophic cardiomyopathy'''. Courtesy of K. Hughes</center></small>]] | [[Image:Case pic 3.jpg|left|thumb|125px|<small><center>'''Histology; hypertrophic cardiomyopathy'''. Courtesy of K. Hughes</center></small>]] | ||
+ | Samples were taken for histological examination (Stained with H and E): | ||
− | The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts). | + | *The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts). |
+ | |||
+ | Some sections were stained with Massons Trichrome: | ||
+ | |||
+ | *This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface. | ||
+ | *Multifocally the fibrosis surrounds individual atrophied myocytes. | ||
+ | *There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries. |
Revision as of 12:02, 31 August 2007
Signalment
- 7 year old
- Male neutered
- Domestic short haired cat
History
- Fully vaccinated
- Sudden death at home
- No other clinical abnormalities
Imaging
Haematology/Biochemistry
Gross Pathology
The following data and pictures were taken at post-mortem examination:
Cardiovascular system:
- Heart has a globoid shape
- Ventricular wall measurements:
- Interventricular septum; 12mm
- Right ventricular wall; 3mm
- Left ventricular wall; 10mm
- Pericardium is fatty, shiny and intact
No embolic thrombi were found in the abdominal aorta.
No further abnormalities were found.
Histopathology
Samples were taken for histological examination (Stained with H and E):
- The cardiac myocytes are multifocally widely spaced and infiltrated by streams of spindle shaped cells (fibroblasts).
Some sections were stained with Massons Trichrome:
- This confirmed the presence of large, multifocal areas of fibrosis within the inner third of the myocardium and extending to the endocardial surface.
- Multifocally the fibrosis surrounds individual atrophied myocytes.
- There is mural thickening (smooth muscle hypertrophy) of the intramyocardial arteries.