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In progressive renal disease, diminished renal reserve → renal insufficiency → renal failure and end stage renal disease.
*Renal insufficiency is seen with loss of 50-70% of the glomerular filtration rate (GFR), azotaemia with loss of >75% of the GFR and renal failure and uraemia when the GFR is below 30%.
==Definitions==
'''Azotaemia''' - condition characterised by abnormal levels of nitrogen containing compounds such as urea and creatinine in the blood. Is one of the clinical characteristics of uraemia. <br /br>
'''Uraemia''' - a clinical syndrome of renal failure in which blood urea levels are higher than normal.
[[Category:Kidney - Pathology]]
[[Category:Kidney - Pathology]]