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*Nuclear chromatin is dense and clumped.
*Nuclear chromatin is dense and clumped.
The cytological interpretation is a well-differentiated hepatic lymphoma.
The cytological interpretation is a well-differentiated hepatic lymphoma.
|l1=
|l1=Lymphoma - Cytology
|q2=Discuss the condition.
|q2=Discuss the condition.
|a2=
|a2=
*Cats with hepatic lymphoma usually have severe hepatomegaly, whereas with lymphocytic periportal hepatitis, hepatomegaly is typically mild. <br><br>
*Cats with hepatic lymphoma usually have severe hepatomegaly, whereas with lymphocytic periportal hepatitis, hepatomegaly is typically mild. <br><br>
Histological confirmation is recommended in cats with severe lymphocytic infiltrates and marked hepatomegaly, regardless of the cytological appearance of the lymphocytes.
Histological confirmation is recommended in cats with severe lymphocytic infiltrates and marked hepatomegaly, regardless of the cytological appearance of the lymphocytes.
|l2=Lymphoma - Cytology
|q3=Discuss the prognosis and treatment options.
|q3=Discuss the prognosis and treatment options.
|a3=Treatment options include chemotherapy. In a few isolated cases where the tumour is localized and easily accessible, surgery or radiation therapy may be used. <br><br>
|a3=Treatment options include chemotherapy. In a few isolated cases where the tumour is localized and easily accessible, surgery or radiation therapy may be used. <br><br>
Cats that are not treated have an average survival time of only 4–6 weeks once the diagnosis has been made. <br><br>
Cats that are not treated have an average survival time of only 4–6 weeks once the diagnosis has been made. <br><br>
Note: As pointed out above, the small lymphocytes illustrated in this case do not have features associated with classical lymphoid malignancy (large numbers of large lymphocytes and lymphoblasts) as is usually seen in the dog. It is important to include well-differentiated or so-called ‘small cell’ lymphoma in your differential diagnosis list in addition to lymphocytic periportal hepatitis when lymphocytes are numerous in a hepatic aspirate.
Note: As pointed out above, the small lymphocytes illustrated in this case do not have features associated with classical lymphoid malignancy (large numbers of large lymphocytes and lymphoblasts) as is usually seen in the dog. It is important to include well-differentiated or so-called ‘small cell’ lymphoma in your differential diagnosis list in addition to lymphocytic periportal hepatitis when lymphocytes are numerous in a hepatic aspirate.
|l3=
|l3=Lymphoma#Treatment
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