Changes

==Roles in the Body==

==Roles in the Body==

Haemoglobin found in the [[Erythrocytes|red blood cells (erythrocytes)]] transports oxygen from the lungs to the tissues. Myoglobin is the primary oxygen transporter in muscle tissues As a component of cytochromes, such as cytochrome c and cytochrome oxidase, iron is also essential for the functioning of the electron transport chain and the production of energy in the form of adenosine triphosphate (ATP). After haem, the [[Liver - Anatomy & Physiology|liver]] contains the largest iron stores, as ferritin or haemosiderin, both of which are iron-containing proteins<ref name="Naigamwalla">Naigamwalla, DZ, Webb, JA, Giger, U (2012). “Iron deficiency anaemia”. Canad. Vet. J. 53:250-256.</ref>. Body stores of iron are tightly regulated to provide adequate supplies for nutritional requirements, while avoiding toxicity from excess. This is achieved primarily by regulating absorption. The biological availability of iron is affected by a number of factors, in particular the chemical form of the [[Iron - Nutrition#Dietary Sources|iron source]]. In addition, some minerals, especially [[Calcium - Nutrition|calcium]], can decrease the absorption of iron so if calcium supplements are being given to the animal it is particularly important to ensure that the dietary iron content is adequate.

Haemoglobin found in the [[Erythrocytes|red blood cells (erythrocytes)]] transports oxygen from the lungs to the tissues. Myoglobin is the primary oxygen transporter in muscle tissues. As a component of cytochromes, such as cytochrome c and cytochrome oxidase, iron is also essential for the functioning of the electron transport chain and the production of energy in the form of adenosine triphosphate (ATP). After haem, the [[Liver - Anatomy & Physiology|liver]] contains the largest iron stores, as ferritin or haemosiderin, both of which are iron-containing proteins<ref name="Naigamwalla">Naigamwalla, DZ, Webb, JA, Giger, U (2012). “Iron deficiency anaemia”. Canad. Vet. J. 53:250-256.</ref>. Body stores of iron are tightly regulated to provide adequate supplies for nutritional requirements, while avoiding toxicity from excess. This is achieved primarily by regulating absorption. The biological availability of iron is affected by a number of factors, in particular the chemical form of the [[Iron - Nutrition#Dietary Sources|iron source]]. In addition, some minerals, especially [[Calcium - Nutrition|calcium]], can decrease the absorption of iron so if calcium supplements are being given to the animal it is particularly important to ensure that the dietary iron content is adequate.

==Consequences of Iron Deficiency==

==Consequences of Iron Deficiency==