Changes

Jump to navigation Jump to search
Line 74: Line 74:  
*Cells:
 
*Cells:
 
**'''Osteoblasts''': single layer of cuboidal cells which synthesize bone extracellular matrix (ECM)
 
**'''Osteoblasts''': single layer of cuboidal cells which synthesize bone extracellular matrix (ECM)
 +
***Basophilic cytoplasm
 +
***When inactive - less cytoplasm -> flattened
 
**'''Osteocytes''': osteoblasts embedded in their own matrix; reside within '''lacunae''' and are interconnected via channels forming '''canaliculi'''
 
**'''Osteocytes''': osteoblasts embedded in their own matrix; reside within '''lacunae''' and are interconnected via channels forming '''canaliculi'''
 
***'''Canaliculi''' create connections to form a huge neural-like junctional organization
 
***'''Canaliculi''' create connections to form a huge neural-like junctional organization
 
**'''Osteoclasts''': giant (multinucleate monocytes) cells which act to resorb bone ECM
 
**'''Osteoclasts''': giant (multinucleate monocytes) cells which act to resorb bone ECM
 +
**Osteoblasts, osteocytes, chondroblasts and chondrocytes are derived from stromal fibroblastic system ('''osteoprogenitor cells'''); osteoclasts from haematopoietic system
    
All mammalian bone is organized as lamellated sheets:
 
All mammalian bone is organized as lamellated sheets:
1,351

edits

Navigation menu