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*Cell wall proteins bind fibronectin and fibrinogen, allowing bacteria to attched to damaged tissues
*Cell wall proteins bind fibronectin and fibrinogen, allowing bacteria to attched to damaged tissues
*Coagulase, DNase and protein A production mark pathogenicity
*Coagulase, DNase and protein A production mark pathogenicity
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*Haemolysins made by ''S. aureus'' and ''S. intermedius'' act as toxins
*Alpha-haemolysin prouces a narrow zone of complete haemolysis; this toxin causes necrosis and targets mast cells and plasma cells, whose contents cause damage
*Beta-haemolysin produces a wide zone of incomplete haemolysis; damages membranes and causes leakage, contributing to necrosis
*Also gamma and delta toxins
*Toxic shock syndrome toxin acts as a superantigen, which causes T cell proliferation and production of cytokines, leading to cardiovascular shock, with microthrombus formation in capillaries
*Enterotoxins produced by some strains of ''S. aureus'' cause food poisoning in humans
*Proteases, hyaluronidases and lipases facilitate survival of bacteria and spread and tissue destruction
===Diagnosis===
===Diagnosis===