<big><center>[[Developmental Biology - Anatomy & Physiology|'''BACK TO DEVELOPMENTAL BIOLOGY]]</center></big>
<big><center>[[Developmental Biology - Anatomy & Physiology|'''BACK TO DEVELOPMENTAL BIOLOGY]]</center></big>
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==Introduction==
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The intermediate mesoderm exists as a strip of tissue between the lateral plate mesoderm and somites. It gives rise to the urinary system and some parts of the reproductive system. Kidney development includes three forms:
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:Pronephros
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:Mesonephros
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:Metanephros
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Mammals develop all three, and continue to use the metanephros in adult life. More primitive animals have only the first one or two.
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==Pronephros==
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*''The earliest kidney. Develops in the anterior of the animal (adjacent to somites 7 - 10). Eliminated in later development''.
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#At intervals along the intermediate mesoderm, dorsal evaginations occur.
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#Evaginations extend caudally and eventually fuse with more caudal evaginations.
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#*The caudal - most evagination fuses with the cloaca.
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#Forms a continuous excretory tube to the cloaca.
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#Capillaries develop at the medial aspect of the intermediate mesoderm so that waste can diffuse from the blood to the excretory channel.
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#Connections between the intermediate mesoderm and somites as well between the intermediate mesoderm and lateral plate mesoderm break down.