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*Viremia
*Viremia
*Virus targets stratum spinosum of stratified squamous epithelia and mucus mebranes
*Virus targets stratum spinosum of stratified squamous epithelia and mucus mebranes
*Secondary [[Cavity & Gingiva - Pathology#Foot and Mouth disease|'''vesicles''']] appear after incubation of 2-14 days
*Secondary [[Foot and Mouth Disease|'''vesicles''']] appear after incubation of 2-14 days
*Appearance of lesions by age:
*Appearance of lesions by age:
**0-2 days: unruptured vesicles
**0-2 days: unruptured vesicles