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Line 40: |
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| − | ===''Rhodococcus equi''=== | + | ===''[[Rhodococcus equi]]''=== |
| − | [[Image:Pyogranulomatous lungs due to Rhodococcus Equi.jpg|right|thumb|100px|<small><center>Pyogranulomatous lesions due to Rhodococcus equi (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]] | |
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| − | *Causative agent [[Rhodococcus equi|''Rhodococcus (Corynebacterium) equi'']]
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| − | *Important cause of sever, often fatal [[Lungs Inflammatory - Pathology#Granulomatous pneumonia|granulomatous]] [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|pneumonia]] in foals
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| − | *Clinical signs include depression, cough, weight loss, respiratory distress, diarrhoea, arthritis, subcutaneous abscesses
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| − | *Bacterium survives phagocytosis and multiplies
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| − | *Bacterial toxins -> caseous necrosis in lungs -> attracts inflammatory cells -> pyogranulomatous pneumonia
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| − | *Grossly:
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| − | **Multiple firm nodules, usually no encapsulation
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| − | **Partial [[Lungs Ventilation - Pathology#Atelectasis (Collapse)|atelectasis]]
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| − | *Histologically:
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| − | **Pyogranulomatous lesions
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| − | **Macrophages with ingested microorganisms in the alveoli
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| − | **Necrosis spreading through parenchyma
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| | ==In Cattle== | | ==In Cattle== |