Changes

*Viraemia

*Viraemia

*Spreads via [[Monocytes|monocytes]] to a variety of epithelium depending upon the strain of virus  

*Spreads via [[Monocytes|monocytes]] to a variety of epithelium depending upon the strain of virus  

*[[Respiratory Viral Infections - Pathology#Canine distemper|Respiratory]] and alimentary tracts, skin and later (1-5 wk. post infection) to the brain

*Respiratory and alimentary tracts, skin and later (1-5 wk. post infection) to the brain

*'''Clinical signs''':

*'''Clinical signs''':

**Mucopurulent oculonasal discharge  

**Mucopurulent oculonasal discharge  

*Live attenuated vaccines may kill some wildlife therefore '''Iscom vaccine''' is used in seal sanctuaries

*Live attenuated vaccines may kill some wildlife therefore '''Iscom vaccine''' is used in seal sanctuaries

====Secondary Concerns====

====Secondary Concerns====

*Can contribute to [[Respiratory Viral Infections - Pathology#In Dogs|Infectious canine tracheitis]]  

*Can contribute to [[Infectious Canine Tracheitis]]  

*May be involved in [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]]

*May be involved in [[Pancreatitis, Chronic Interstitial|chronic interstitial pancreatitis]]

*May cause [[Bones Developmental - Pathology#Retention of elongated primary trabeculae|growth retardation lattice]]  

*May cause [[Bones Developmental - Pathology#Retention of elongated primary trabeculae|growth retardation lattice]]