Changes

[[Image:virusimmunity.jpg|thumb|300px|right|'''''']]

[[Image:virusimmunity.jpg|thumb|350px|right|'''''']]

The cell-mediated response to viruses involves [[Lymphocytes#Cytotoxic CD8+|CD8+ T-cell]] mediated killing of virus infected cells. They are the main cells involved in the immune response to '''intracellular''' virus infection. Viruses are detected by the recognition of [[Major Histocompatability Complexes#MHC I|MHC I]]-peptide complex and infected cells are killed by apoptosis. perforin and granzymes activate the caspase cascade and Fas-ligand triggers the Fas-mediated apoptosis pathway. Cytotoxic [[Cytokines|cytokines]] (especially TNF-α & TNF-β lymphotoxin) act on TNF receptors to induce programmed cell death.

The cell-mediated response to viruses involves [[Lymphocytes#Cytotoxic CD8+|CD8+ T-cell]] mediated killing of virus infected cells. They are the main cells involved in the immune response to '''intracellular''' virus infection. Viruses are detected by the recognition of [[Major Histocompatability Complexes#MHC I|MHC I]]-peptide complex and infected cells are killed by apoptosis. perforin and granzymes activate the caspase cascade and Fas-ligand triggers the Fas-mediated apoptosis pathway. Cytotoxic [[Cytokines|cytokines]] (especially TNF-α & TNF-β lymphotoxin) act on TNF receptors to induce programmed cell death.

<big>'''Also see [[Immunity to Viruses]]'''</big>

<big>'''Also see [[Immunity to Viruses]]'''</big>

[[Category:To Do - AimeeHicks]]

[[Category:To Do - AimeeHicks]][[Category:To Do - Review]]

[[Category:Adaptive Immune System]]

[[Category:Adaptive Immune System]]