Changes

====The binding of soluble lectins to pathogens====  

====The binding of soluble lectins to pathogens====  

*#* E.g. collectins.

 

*#* Lectins are proteins that bind carbohydrates, in this case carbohydrates that have a terminal mannose residue – they are called mannose-binding lectins and are secreted by the liver into plasma. This action of lectin binding to carbohydrate activates plasma-associated proteases called mannose-binding lectin associated proteases (MASPs), these act on C4 and C2 in the same way as C1 esterase.

* E.g. collectins.

* Lectins are proteins that bind carbohydrates.

** In this case, they bind carbohydrates that have a terminal mannose residue.

*** They are called mannose-binding lectins.

*** Are secreted by the liver into plasma.  

* The action of lectin binding to carbohydrate activates plasma-associated proteases called mannose-binding lectin associated proteases (MASPs).

** These act on C4 and C2 in the same way as C1 esterase.

==MEMBRANE ATTACK COMPLEX==

==MEMBRANE ATTACK COMPLEX==