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Congenital Panhypopituitarism (view source)
Revision as of 18:43, 27 February 2011
, 18:43, 27 February 2011no edit summary
*Rare in animals, reported in German Shepherd Dogs
*Deficiency of growth hormone
*Proportionate dwarfism
*Growth plates remain open for up to 4 years
*Disorganised proliferating chondrocytes
Also known as ''Pituitary Dwarfism'', Congenital Panhypopituitarism is defined by failure of differentiation of oesophageal ectoderm from which the pituitary is derived. The pituitary is replaced by a cystic dilatation of ''Rathke's Cleft'' which replaces normal tissue with multilocular cysts- lined with non-secretory cuboidal epithelium.
Also known as ''Pituitary Dwarfism'', Congenital Panhypopituitarism is defined by failure of differentiation of oesophageal ectoderm from which the pituitary is derived. The pituitary is replaced by a cystic dilatation of ''Rathke's Cleft'' which replaces normal tissue with multilocular cysts- lined with non-secretory cuboidal epithelium.
[[Image:Pituitary dwarfism.jpg|right|thumb|125px|<small><center>'''Cystic Rathke's Pouch'''. Courtesy of A. Jefferies</center></small>]]
[[Image:Pituitary dwarfism.jpg|right|thumb|125px|<small><center>'''Cystic Rathke's Pouch'''. Courtesy of A. Jefferies</center></small>]]
[[Category:Pituitary Gland - Pathology]]
[[Category:Pituitary Gland - Pathology]]
[[Category:Bones - Metabolic Pathology]]