Difference between revisions of "Hyperthyroidism"
Jump to navigation
Jump to search
| Line 28: | Line 28: | ||
*'''Radioactive iodine''' therapy. Useful for intrathoracic thyroid nodules. | *'''Radioactive iodine''' therapy. Useful for intrathoracic thyroid nodules. | ||
| + | |||
| + | *In young animals causes accelerated maturation of growth plate | ||
| + | *In adults causes [[Bones Degenerative - Pathology#Osteoporosis (Atrophy)|osteoporosis]] | ||
| Line 57: | Line 60: | ||
[[Category:To Do - Clinical]][[Category:Endocrine Diseases - Cat]] | [[Category:To Do - Clinical]][[Category:Endocrine Diseases - Cat]] | ||
| − | + | [[Category:Bones - Metabolic Pathology]] | |
[[Category:Thyroid Gland - Pathology]] | [[Category:Thyroid Gland - Pathology]] | ||
Revision as of 18:48, 27 February 2011
 |
This article is still under construction. |
Seen most commonly in the cat. Elderly cats are affected with the average age of onset being 12-13 years.
Clinical signs:
- Weight loss despite polyphagia
- Increased activity, nervousness (approximately 10% will show apathy)
- Polyuria and polydipsia
- Heat intolerance, panting
- Tachycardia >240 bpm
- Poor coat, matted and unkempt
- Palpable thyroid mass often present
Often see a hypertrophic cardiomyopathy due to chronically increased heart rate and activity.
Aetiopathogenesis:
>98% are a functional adenoma of the thyroid gland and many will be palpable.
Treatment:
Surgical removal of the affected thyroid gland(s). If bilateral it is important to preserve at least one parathyroid gland to maintain calcium homeostasis.
Medical treatment:
- Carbamizole: Interferes with thyroid hormone synthesis.
- Radioactive iodine therapy. Useful for intrathoracic thyroid nodules.
- In young animals causes accelerated maturation of growth plate
- In adults causes osteoporosis
Pathophysiology
Signalment
Presentation/Clinical Signs
- Weight loss
- Cardiovascular effects
- Palpable goitre
- Hyperactive
- Polyuria
- Polydipsia
Diagnosis
- T4 Assay
- T4 and TSH assay
Treatment
- Surgical - Thyroidectomy
- Medical - Thiamazole blocks synthesis of T3 and T4.
- Radioactive Iodine