Difference between revisions of "Muscles Inflammatory - Pathology"

Revision as of 19:04, 3 March 2011

In Golden retrievers
Very rare
Clinical signs:
- Acute bilateral exophthalmos
Involves only extraocular muscles except for retractor blbi
Grossly:
- Swollen and pale extraocular muscles
Histologically:
- Sterile myositis
- Multifocal necrosis of myofibres
- Lymphocytic, histiocytic and plasmacytic infiltrate with few neutrophils

Unknown aetiology
Major cell involved is eosinphil
Usually noticed at slaughter - green muscle discoloration
May be caused by degenteration of Sarcocystis spp.
Grossly:
- Green discolored areas, well demarcated
- Mostly in muscles of back and thighs
Histologically:
- Massive eosinophil infiltration
- Muscle fibres may degenerate
- In old lesions - endimysial fibrosis, myofibre atrophy, some regeneration, lymphocytes, plasma cells, macrophages and few eosinophils
- Capsule may form

@@ Line 19: / Line 19: @@
-===Idiopathic myositis===
+===[[Idiopathic Myositis]]===
-====Canine polymyositis====
+====[[Canine Polymyositis]]====
-*DOES NOT include [[Masticatory Muscle Myositis]]
-*Rare
-*Clinical signs:
-**Muscle pain
-**Fever
-**Weakness, particularly in hind limbs
-*Grossly:
-**Inflammation is accompanied by muscle necrosis and regeneration
-*Histologically:
-**Inflammatory foci with lymphocytes, plasma cells and occasionally eosinophils
-*Possibly immunological cause
-*Single biopsy may not be enough to make the diagnosis as it tends to be multifocal and disseminated
-*Lesions similar to some infectious causes (such as ''[[Toxoplasma gondii]]'')
-[[Category:Muscles - Inflammatory Pathology]]
@@ Line 77: / Line 61: @@
 [[Category:Muscles - Inflammatory Pathology]]
+[[Category:Muscles - Inflammatory Pathology]]
-[[Category:Musculoskeletal System - Pathology]]