Difference between revisions of "Chlamydia and Chlamydophila species"
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*May cause [[Joints - inflammatory#In Sheep|arthritis in sheep]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]] | *May cause [[Joints - inflammatory#In Sheep|arthritis in sheep]] and [[Joints - inflammatory#In Cattle|arthritis in cattle]] | ||
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| + | ===Overview=== | ||
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| + | ===Characteristics=== | ||
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| + | *Obligate intracellular bacteria | ||
| + | *Gram negative bacteria with outer membrane, LPS, ribosomes, DNA and RNA | ||
| + | *Peptidoglycan cell wall resistant to lysozyme | ||
| + | *Only grow in presence of living eukaryotic cells | ||
| + | *Unable to synthesis ATP therefore require intermediates from host cells | ||
| + | * | ||
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| + | ===Pathogenesis and pathogenicity=== | ||
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| + | *Elementary body, the infective form, phagocytosed and internalised into host epithelial cells | ||
| + | *Transformation into larger reticulate body | ||
| + | *Reticulate body divides by binary fission to form many new chlamydia cells | ||
| + | *Reticulate body has un-crosslinked peptidoglycan, which is cross-linked to form elementary bodies | ||
| + | *Elementary bodies released from dying host cells to infect other cells | ||
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| + | ===Clinical infections=== | ||
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| + | ===Diagnosis=== | ||
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| + | ===Treatments=== | ||
Revision as of 09:08, 18 May 2008
Chlamydophila psittaci involved in feline rhinotracheitis together with herpes virus 1 C.psittaci more frequently infects the conjunctival epithelium -> chronic conjunctivitis, see feline chlamydiosis
- May cause arthritis in sheep and arthritis in cattle
Overview
Characteristics
- Obligate intracellular bacteria
- Gram negative bacteria with outer membrane, LPS, ribosomes, DNA and RNA
- Peptidoglycan cell wall resistant to lysozyme
- Only grow in presence of living eukaryotic cells
- Unable to synthesis ATP therefore require intermediates from host cells
Pathogenesis and pathogenicity
- Elementary body, the infective form, phagocytosed and internalised into host epithelial cells
- Transformation into larger reticulate body
- Reticulate body divides by binary fission to form many new chlamydia cells
- Reticulate body has un-crosslinked peptidoglycan, which is cross-linked to form elementary bodies
- Elementary bodies released from dying host cells to infect other cells