Difference between revisions of "Clostridium species"

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<big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big>
 
<big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big>
  
==Clostridia==
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===Overview===
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*Organisms present in the soil, alimentary tract and faeces
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*Endospores may be present in liver and may be reactivated to cause disease
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*Neurotoxic clostridia, ''Clostridium tetani'' and ''Clostridium botulinum'' affect neuromuscular function but cause no tissue damage
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*Histotoxic clostridia cause localised lesions in tissues and may cause toxaemia
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*''C. perfringens'' cause inflammatory lesions in the gastrointestinal tract and enterotoxaemia
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===Characteristics===
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*Large Gram-positive rods
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*Obligate anaerobes
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*Fermentative, catalase negative, oxidase negative
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*Straight or slightly curved
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*Motile by flagellae
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*Require enriched media for growth
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*Produce endospores which vary in shape and location and cause bulging of mother cell
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===Pathogenesis and pathogenicity===
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*''C. perfringens'' colonies are surrounded by a zone of double haemolysis
  
* ''Clostrisium'' bacteria are Gram-positive and obligate anaerobes.
 
  
==Species==
 
  
 
===Clostridium botulinum===
 
===Clostridium botulinum===

Revision as of 14:05, 18 May 2008

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BACK TO BACTERIA

Overview

  • Organisms present in the soil, alimentary tract and faeces
  • Endospores may be present in liver and may be reactivated to cause disease
  • Neurotoxic clostridia, Clostridium tetani and Clostridium botulinum affect neuromuscular function but cause no tissue damage
  • Histotoxic clostridia cause localised lesions in tissues and may cause toxaemia
  • C. perfringens cause inflammatory lesions in the gastrointestinal tract and enterotoxaemia

Characteristics

  • Large Gram-positive rods
  • Obligate anaerobes
  • Fermentative, catalase negative, oxidase negative
  • Straight or slightly curved
  • Motile by flagellae
  • Require enriched media for growth
  • Produce endospores which vary in shape and location and cause bulging of mother cell


Pathogenesis and pathogenicity

  • C. perfringens colonies are surrounded by a zone of double haemolysis


Clostridium botulinum

  • Clostridium botulinum has been implicated in equine grass sickness.
  • The toxin also causes botulism, a disease affecting muscle at the neuromuscular junction.

Clostridium chauvei

Clostridium novyi

Clostridium perfringens

Clostridium septicum

Clostridium sordelli

Clostridium tetani

  • Clostridium tetani may infect wounds, giving rise to tetanus