Difference between revisions of "Sexual Differentiation - Anatomy & Physiology"

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* Established at the time of '''fertilisation'''.
 
* Established at the time of '''fertilisation'''.
 
* The foetus receives its genetic endowment in two equal portions from the male gamete ('''Spermatozoon''') and female gamete ('''Oocyte''').
 
* The foetus receives its genetic endowment in two equal portions from the male gamete ('''Spermatozoon''') and female gamete ('''Oocyte''').
* The X sex chromasome is larger than the Y sex chromasome.
+
* The X sex chromosome is larger than the Y sex chromosome.
* '''Females''' have XX chromasomes.  All oocytes contain one X chromasome, they are the '''homogametic''' sex.
+
* '''Females''' have XX chromosomes.  All oocytes contain one X chromosome, they are the '''homogametic''' sex.
* '''Males''' have XY chromasomes.  Spermatozoa form two distinct populations, one containing X chromasomes and one containing Y chromasomes.  They are the '''heterogametic''' sex.
+
* '''Males''' have XY chromosomes.  Spermatozoa form two distinct populations, one containing X chromosomes and one containing Y chromosomes.  They are the '''heterogametic''' sex.
 +
 
 +
* The '''Y''' chromosome is required to '''initiate male development'''.
 +
* In absence of the Y chromosome, female gonads (Ovaries) will develop.
 +
* The prime male determining gene is '''SRY''' (sex determining region of the Y chromosome).  SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes
 +
* The presence of SRY alone is sufficient to ensure development of male gonads (Testes).
  
 
== Internal Genetalia ==
 
== Internal Genetalia ==

Revision as of 09:20, 3 July 2008

Genetic Sex

  • Established at the time of fertilisation.
  • The foetus receives its genetic endowment in two equal portions from the male gamete (Spermatozoon) and female gamete (Oocyte).
  • The X sex chromosome is larger than the Y sex chromosome.
  • Females have XX chromosomes. All oocytes contain one X chromosome, they are the homogametic sex.
  • Males have XY chromosomes. Spermatozoa form two distinct populations, one containing X chromosomes and one containing Y chromosomes. They are the heterogametic sex.
  • The Y chromosome is required to initiate male development.
  • In absence of the Y chromosome, female gonads (Ovaries) will develop.
  • The prime male determining gene is SRY (sex determining region of the Y chromosome). SRY is a very small piece of DNA that acts as a molecular switch to regulate structural genes and autosomal chromosomes
  • The presence of SRY alone is sufficient to ensure development of male gonads (Testes).

Internal Genetalia

External Genetalia

Turner's Syndrome
Kleinfelter's Syndrome
Testicular Feminisation
Adrenogenital Syndrome
Bovine Freemartinism