Difference between revisions of "Angiotensin Converting Enzyme"

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It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary ciculation and this is therefore, the site of action of the ACE inhibitor drugs.
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It is very important in the [[Renin Angiotensin Aldosterone System|Renin Angiotensin Aldosterone System (RAAS)]]. ACE is predominantly expressed on epithelial cell membranes in the pulmonary circulation and this is therefore, the site of action of the ACE inhibitor drugs.
  
  

Latest revision as of 08:15, 20 October 2016


Overview

Angiotensin converting enzyme is known as ACE. It is a membrane bound metalloproteinase and converts Angiotensin 1 to Angiotensin 2.

Fvasconcellos 2006, Spacefilling models of angiotensin I (left) and angiotensin II (right).


It is very important in the Renin Angiotensin Aldosterone System (RAAS). ACE is predominantly expressed on epithelial cell membranes in the pulmonary circulation and this is therefore, the site of action of the ACE inhibitor drugs.



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