2,232
edits
Changes
Aquaporins of the Kidney and Water Homeostasis - Anatomy & Physiology (view source)
Revision as of 17:08, 14 August 2008
, 17:08, 14 August 2008no edit summary
** <Font Color="#9900ff">'''Function Unknown'''</Font>
** <Font Color="#9900ff">'''Function Unknown'''</Font>
* They allow the reabsorption of water, glycerol and chlorine from the filtrate
* They allow the reabsorption of water, glycerol and chlorine from the filtrate
* Without them producing concentrated urine would be impossible
* Without them producing concentrated urine would be impossible
==[[Endocrine System - Pituitary Gland - Anatomy & Physiology #Posterior Pituitary Gland| ADH]]==
* AQP2 is stored in vesicle membranes within the [[Collecting Duct - Anatomy & Physiology #Principal Cells| principal cells]] of the [[Collecting Duct - Anatomy & Physiology| collecting ducts]]
* AQP2 is stored in vesicle membranes within the [[Collecting Duct - Anatomy & Physiology #Principal Cells| principal cells]] of the [[Collecting Duct - Anatomy & Physiology| collecting ducts]]
* [[Endocrine System - Pituitary Gland - Anatomy & Physiology #Posterior Pituitary Gland| ADH]] causes these vesicles to attach to the principal cell membranes.
* [[Endocrine System - Pituitary Gland - Anatomy & Physiology #Posterior Pituitary Gland| ADH]] causes these vesicles to attach to the principal cell membranes.
** The higher its concentration the more AQP2 bind to principal cell membranes therefore the more AQP2 available to water within the collecting duct
** The higher its concentration the more AQP2 bind to principal cell membranes therefore the more AQP2 available to water within the collecting duct
** The more water is reabsorbed
** The more water is reabsorbed
** Thanks to the gradient created by the hypertonic medulla which is present due to the countercurrent multiplier in the [[Loop Of Henle - Anatomy & Physiology| Loop of Henle]]
** Thanks to the gradient created by the hypertonic medulla which is present due to the countercurrent multiplier in the [[Loop Of Henle - Anatomy & Physiology| Loop of Henle]]
* This system allows both concentrated and dilute urine to be produced depending on ADH secretion and therefore the density of aquaporins in the principal cell membranes
* This system allows both concentrated and dilute urine to be produced depending on ADH secretion and therefore the density of aquaporins in the principal cell membranes
* Without ADH the collecting duct would remain impermeable to water and as a result water and salt would be lost and wasted.
* This would result in an increase in plasma osmolarity
==Species Variation of the Ability to Conserve Water==
==Species Variation of the Ability to Conserve Water==