Difference between revisions of "EPI"
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*Most common in dog - usually associated with [[Pancreas - degenerative|pancreatic atrophy]] or [[Pancreas - inflammatory#Chronic Pancreatitis|chronic pancreatitis]] | *Most common in dog - usually associated with [[Pancreas - degenerative|pancreatic atrophy]] or [[Pancreas - inflammatory#Chronic Pancreatitis|chronic pancreatitis]] | ||
*Occurs occasionally in other species, esp. calves with [[Pancreas - developmental#Pancreatic hypoplasia|pancreatic hypoplasia]] and in cats | *Occurs occasionally in other species, esp. calves with [[Pancreas - developmental#Pancreatic hypoplasia|pancreatic hypoplasia]] and in cats | ||
| + | *'''Clinical signs''' | ||
| + | **Steatorrhoea | ||
| + | **Diarrhoea | ||
| + | **Weight loss | ||
| + | **Increased appetite | ||
| + | |||
| + | *In contrast, '''horses''' with very little pancreatic tissue develop '''hypoinsulinism''' but rarely EPI | ||
Revision as of 09:53, 7 August 2007
- Exocrine pancreatic insufficiency (EPI) is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas
- Leading to insufficient activity of digestive enzymes in the lumen of the small intestine
- Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI
- Most common in dog - usually associated with pancreatic atrophy or chronic pancreatitis
- Occurs occasionally in other species, esp. calves with pancreatic hypoplasia and in cats
- Clinical signs
- Steatorrhoea
- Diarrhoea
- Weight loss
- Increased appetite
- In contrast, horses with very little pancreatic tissue develop hypoinsulinism but rarely EPI