Difference between revisions of "Vaccines"
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==What do we vaccinate with?== | ==What do we vaccinate with?== | ||
| − | + | [[Image:Passive Immunisation.jpg|thumb|right|150px|Passive Immunisation - Copyright nabrown RVC]] | |
'''Passive immunisation''' | '''Passive immunisation''' | ||
*Administer antibodies | *Administer antibodies | ||
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**Subunit antigens | **Subunit antigens | ||
**DNA | **DNA | ||
| − | + | [[Image:Active Immunisation.jpg|thumb|right|150px|Active Immunisation - Copyright nabrown RVC]] | |
*Delay in protection | *Delay in protection | ||
Revision as of 16:11, 25 August 2008
Why Vaccinate?
- To protect against infectious diseases
- Where there is no effective treatment once infected
- E.g. FeLV, FIV
- Where disease is life-threatening
- E.g. Canine Parvovirus
- To prevent the spread of disease
- E.g. Rabies, FMDV
How do we vaccinate?
- Usually by subcutaneous injection for systemic protection (IgG)
- For mucosal immune reponse, intranasal administration is best (IgA)
What do we vaccinate with?
Passive immunisation
- Administer antibodies
- Maternally-derived antibodies in colostrum
- Antiserum (artificial)
- Immediate protection
- Short duration of action
Active immunisation
- Administer antigen so the patient's own antibodies protect against disease
- Living organisms
- Dead organisms
- Toxoids
- Subunit antigens
- DNA
- Delay in protection
- Often needs two or more doses
- Long duration of action