Difference between revisions of "Exocrine Pancreatic Insufficiency"

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<big><center>[[Pancreas Developmental - Pathology|'''BACK TO PANCREAS - DEVELOPMENTAL''']]</center></big>
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<big><center>[[Pancreas Degenerative - Pathology|'''BACK TO PANCREAS - DEGENERATIVE''']]</center></big>
 
<big><center>[[Pancreas Inflammatory - Pathology|'''BACK TO PANCREAS - INFLAMMATORY''']]</center></big>
 
<big><center>[[Pancreas Hyperplastic and Neoplastic - Pathology|'''BACK TO PANCREAS - HYPERPLASTIC AND NEOPLASTIC''']]</center></big>
 
  
 
*'''Exocrine pancreatic insufficiency (EPI)''' is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas
 
*'''Exocrine pancreatic insufficiency (EPI)''' is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas

Revision as of 11:42, 7 August 2009




  • Exocrine pancreatic insufficiency (EPI) is a syndrome caused by insufficient synthesis and secretion of digestive enzymes by the exocrine portion of the pancreas
  • Leading to insufficient activity of digestive enzymes in the lumen of the small intestine
  • Pancreas has considerable functional reserve, large proportion needs to be non-functional to show signs of EPI
  • Most common in dog - usually associated with pancreatic atrophy or chronic pancreatitis
  • Occurs occasionally in other species, esp. calves with pancreatic hypoplasia and in cats
  • Clinical signs
    • Steatorrhoea
    • Diarrhoea
    • Weight loss
    • Increased appetite
  • In contrast, horses with very little pancreatic tissue develop hypoinsulinism but rarely EPI