Difference between revisions of "Category:Corynebacterium species"

Revision as of 12:44, 12 May 2010

Pyogenic causing suppurative infections except for C. bovis
C. pseudotuberculosis:
- Facultative intracellular pathogen inside macrophages
- Cell wall lipid
- Produces a phospholipase toxin which hydolyses sphingomyelin in mammalian cell membranes
- Phospholipase may enhance survival and multiplication in host in early stages
C. renale
- Urinary tract pathogens
- Produce urease and hydrolyse urea
- Possess fimbriae for attachment to urogenital mucosa
- Infection when immunity reduced or following tissue damage during parturition

Subclinical mastitis in cattle
Found in teat cistern
Causes mild neutrophil response in teat canal of healthy dairy cows and may protect against invasion from more pathogenic bacteria

Samples include pus, exudate, affected tissues and urine
Presence of coryneform organisms in smears
Culture on blood agar, selective blood agar and MacConkey agar
Do not grow on MacConkey
Colony characteristics:
- C. bovis: lipophilic bacterium; small, white, dry, non-haemolytic colonies on plates inoculated with bovine milk
- C. kutscheri: white colonies; occasionally haemolytic
- C. pseudotuberculosis: small, white coloniess surrounded by narrow zone of complete haemolysis; colonies become dry and cream-coloured
- C. renale: small, non-haemolytic colonies after 24 hours; pigment produced after 48 hours
Biochemical reactions:
- Certain strains of C. pseudotuberculosis reduce nitrates
- All pathogenic strains except C. bovis produce urease
Enhancement of haemolysis produced by C. pseudotuberculosis when inoculated across a streak of Rhodococcus equi

The following 5 pages are in this category, out of 5 total.

@@ Line 38: / Line 38: @@
-===''Corynebacterium renale''===
+===''[[Corynebacterium renale]]''===
-*''C. renale, C. pilosum, C. cystitidis''
-*Found in the vulva, vagina and prepuce of normal cattle
-*Bovine pyelonephritis
-**Stress of parturition and short urethra predisposes cows to urinary tract infection
-**Cystitis especially with ''C. cystitidis
-**Ascending infection from bladder through ureters causes pyelonephritis
-**Fever, anoexia, decreased milk production
-**Restlessness; kicking of abdomen indicate renal pain
-**Dysuria, arched back, bloody urine
-**Chronic infection causes extensive renal damage
-**Enlarged ureters and kidneys palpated per rectum
-**Culture from urine; protein and red blood cells in urine
-**Antibiotics e.g. penicillin for at least three weeks
-*Ulcerative balanoposthitis (pizzle rot):
-**Common in Merino sheep and Angora goats
-**Ulceration around prepucial orifice with brown crust, and occasionally on vulva of ewes
-**Bacteria hydrolyse urea to ammonia which causes mucosal irritation and ulceration
-**High urine urea level, from high protein intake may predispose to condition
-**High oestrogen levels in pastures also predisposes
-**Castration and heavy wool around the prepuce are risk factors