Difference between revisions of "Newcastle Disease Virus"
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| Line 15: | Line 15: | ||
*Animal test: | *Animal test: | ||
**Samples of trachea and gut of 20 birds are tested in eggs | **Samples of trachea and gut of 20 birds are tested in eggs | ||
| − | **'''HI''' using anti-NDV serum (to differentiate '''HA''' caused by [[ | + | **'''HI''' using anti-NDV serum (to differentiate '''HA''' caused by [[Avian Influenza]] |
**Virulence of isolate tested by the speed it kills chicks | **Virulence of isolate tested by the speed it kills chicks | ||
*DNA test (which will soon replace the animal test): | *DNA test (which will soon replace the animal test): | ||
**Sequencing the cleavage site of H gene | **Sequencing the cleavage site of H gene | ||
**The more basic amino acids the more virulent the virus | **The more basic amino acids the more virulent the virus | ||
| + | |||
====Control==== | ====Control==== | ||
*Newcastle Disease is '''NOTIFIABLE''' | *Newcastle Disease is '''NOTIFIABLE''' | ||
Revision as of 11:20, 22 May 2010
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This article is still under construction. |
Also known as NDV
Hosts
- Gallinaceous birds, pigeons, parrots, finches
- Subclinical carriers: ducks, ostriches
- Causes conjunctivitis in humans
Pathogenesis
- Transmission via aerosol and direct contact
- Disease ranges from subclinical respiratory tract infections -> torticollis -> haemorrhages and death
Diagnosis
Two diagnostic tests currently exist:
- Animal test:
- Samples of trachea and gut of 20 birds are tested in eggs
- HI using anti-NDV serum (to differentiate HA caused by Avian Influenza
- Virulence of isolate tested by the speed it kills chicks
- DNA test (which will soon replace the animal test):
- Sequencing the cleavage site of H gene
- The more basic amino acids the more virulent the virus
Control
- Newcastle Disease is NOTIFIABLE
- Vaccination of chickens and racing pigeons
- Surveillance of imported exotic birds
- Isolation of infected stock
- Infected premises to be culled and firebreak cull if spread