Difference between revisions of "Canine Parvovirus"
Jump to navigation
Jump to search
| Line 1: | Line 1: | ||
{{unfinished}} | {{unfinished}} | ||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
====Antigenicity==== | ====Antigenicity==== | ||
| Line 43: | Line 34: | ||
*Vaccination, usually in combination with distemper and hepatitis. With first vaccination at 8-10 weeks and the second vaccination two weeks after the first, 10-12 weeks. | *Vaccination, usually in combination with distemper and hepatitis. With first vaccination at 8-10 weeks and the second vaccination two weeks after the first, 10-12 weeks. | ||
*Thorough disinfection after disease | *Thorough disinfection after disease | ||
| + | [[Category:Parvoviridae]][[Category:Dog]] | ||
Revision as of 11:20, 23 May 2010
 |
This article is still under construction. |
Antigenicity
- 2 Canine Viruses:
- Canine Parvovirus 1 (CPV1): avirulent, ubiquitous in canine population
- Canine Parvovirus 2 (CPV2): new virus emerged in the late 1970's
- Antigenic variants occur
Hosts
- Dogs
- CPV 2a/2b can cause disease in cats
Pathogenesis
- Oropharyngeal infection followed by viremia
- 2 distinct syndromes:
- Myocarditis in puppies aged 3-8 weeks
- Virus targets rapidly dividing myocardium
- Sudden death, fading puppy syndrome
- Now rare due to widespread passive immunity
- Enteritis in puppies >8 weeks of age
- Virus targets intestinal crypts
- Villi shorten, then destruction of cypt cells
- Gray, persistent, foul-smelling diarrhoea or hemorrhagic enteritis
- High morbidity, low mortality (10%)
Epidemiology
- Orofecal transmission
- Host range is controlled by only a few amino acids
Diagnosis
- HA or ELISA for virus
Control
- Vaccination, usually in combination with distemper and hepatitis. With first vaccination at 8-10 weeks and the second vaccination two weeks after the first, 10-12 weeks.
- Thorough disinfection after disease