Difference between revisions of "Category:Liver - Degenerative Pathology"
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===associated with derangement of carbohydrate metabolism=== | ===associated with derangement of carbohydrate metabolism=== |
Revision as of 12:55, 7 June 2010
Liver - Degenerative Pathology
associated with derangement of carbohydrate metabolism
Diabetes mellitus
- where there is insufficient insulin or a decrease in number of insulin receptors in cells
- seen mostly in dogs
- produces a markedly fatty liver due to release of fat from the fat stores for use as an energy source
Ketosis
- due to an excessive drain on carbohydrate stores because pregnant and lactating animals have a continuous demand for glucose
- ketosis results when fat metabolism which occurs in response to the increased energy demand is excessive
- ketone bodies accumulate in the blood and there is marked fatty change in the liver
- can occur in starvation but commonly seen in two conditions in livestock:
ketosis of cattle (acetonemia)
- occurs in high yielding dairy cows a few weeks postpartum
- due to excessive loss of glucose in the milk
- milk yield drops
- smell of ketones on the breath
- ketones excreted in the milk
- self-limiting condition
pregnancy toxaemia in sheep
- occurs in ewes in late pregnancy carrying twin lambs 'twin lamb disease'
- drain of carbohydrate stores is due to rapidly growing foetuses
- serious condition and highly fatal
- clinical signs (neurological)
- apparent blindness
- dullness
- convulsions
- coma
- sequelae
- foetuses die
- apparent recovery in ewe until toxaemia from the decomposing foetuses results in the ewe's death
associated with anoxia and toxaemia
anoxia
- passive congestion
- anaemias
toxaemia
- toxins absorbed from the gut interfere with many stages of triglyceride metabolism
Pages in category "Liver - Degenerative Pathology"
The following 9 pages are in this category, out of 9 total.