Difference between revisions of "Immunoglobulins Flashcards"
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|a6=Helps B cell development | |a6=Helps B cell development | ||
− | |l6=Immunoglobulin D | + | |l6=Immunoglobulin D#Function |
|q7=True or False: IgE is not a soluble antibody? | |q7=True or False: IgE is not a soluble antibody? | ||
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Revision as of 16:25, 12 June 2010
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Immunoglobulins Structure and Function
Question | Answer | Article | |
What are immunoglobulins also known as? | Antibodies
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Link to Article | |
How many domains does the heavy chain have? |
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Link to Article | |
How many domains does the light chain have? |
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Link to Article | |
What are hypervariable domains? |
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Link to Article | |
What does Fab stand for and from which chain is it generated? |
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Link to Article | |
What does Fc stand for and from which chain is it generated? |
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Link to Article | |
What does the Fc fragment do? | Mediates phagocytosis
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Link to Article | |
What are the four major effects of antibodies? |
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Link to Article |
Classes of Immunoglobulin
Question | Answer | Article | |
How do the five classes of immunoglobulins vary from each other? | They each have a different composition to their heavy chains
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Link to Article | |
IgA is specially adapted for function at which type of surface? | Mucosal surfaces
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Link to Article | |
True or False: IgA is a monomer |
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Link to Article | |
What are the functions of IgA? |
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Link to Article | |
In which species has IgD been identified? |
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Link to Article | |
What is the main function of IgD? | Helps B cell development
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Link to Article | |
True or False: IgE is not a soluble antibody? | True
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Link to Article | |
What are the functions of IgE? |
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Link to Article | |
True or False: IgG is the smallest antibody and can easily leave the plasma and enter tissue? | True
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Link to Article | |
Where is IgG produced? | Bone marrow
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Link to Article | |
What is the function of IgG? | Activates the classical pathway of the complement cascade
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Link to Article | |
True or False: IgM is a monomer |
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Link to Article | |
IgM is five times larger than most other antibodies. What effect does this have on its function? |
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Link to Article | |
What are the main functions of IgM? |
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Link to Article |
Immunoglobulins Variation
Question | Answer | Article | |
Which genes code for the immunoglobulin subtypes and on which chain are they located? |
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Link to Article | |
Complete the sentences about IgG subtypes:
Humans and rodents have ??? IgG subtypes. Dogs have ??? IgG subtypes. Ruminats have ??? IgG subtypes. |
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Link to Article | |
What are allotypes? |
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Link to Article | |
What are idiotypes? | Variations in the sequences of amino acids in the variable regions of the light and heavy chains
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Link to Article | |
What is immunoglobulin heavy chain switching? |
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Link to Article | |
How do different classes of antibody differ from each other? |
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Link to Article |