Difference between revisions of "Gastric Squamous Cell Carcinoma - Horse"
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| − | Squamous cell carcinoma is the most common tumor of the equine stomach.<ref name="Olsen">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref>. It can affect the cardia and upper squamous regions of the stomach, resulting in a persistent mild [[Colic Diagnosis - Clinical Signs|colic]], commonly seen soon after feeding. The tumor can invade and metastasize to lymph nodes, the lungs and regions palpable on [[Colic Diagnosis - Rectal Examination|rectal examination]].<ref name="Olsen">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref> The main clinical signs include '''weight loss''' and general ill health.(Merck) '''Hypertrophic osteopathy''' associated with this neoplastic disease has been reported in one horse.<ref>Schleining, J.A, Voss, E.D (2004) Hypertophic osteopathy secondary to gastric squamous cell carcinoma in a horse. ''Equine Vet Educ'', 16:304-307. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref> Diagnosis is made by exclusion of other causes of weight loss and gastroscopy. In most cases, surgical resection is not possible<ref>East, L.M, Savage, C.J (1998) Abdominal neoplasia (excluding urogenital tract). ''Vet Clin North Am Equine Pract'', 14:475-493. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref> and the prognosis is grave. | + | ==Description== |
| + | Squamous cell carcinoma is the most common tumor of the equine stomach.<ref name="Olsen">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref>. It can affect the cardia and upper squamous regions of the stomach, resulting in a persistent mild [[Colic Diagnosis - Clinical Signs|colic]], commonly seen soon after feeding. The tumor can invade and metastasize to lymph nodes, the lungs and regions palpable on [[Colic Diagnosis - Rectal Examination|rectal examination]].<ref name="Olsen">Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. ''Vet Rec'', 131:170-173. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref> | ||
| + | |||
| + | ==Clinical Signs and Diagnosis== | ||
| + | The main clinical signs include '''weight loss''' and general ill health.(Merck) '''Hypertrophic osteopathy''' associated with this neoplastic disease has been reported in one horse.<ref>Schleining, J.A, Voss, E.D (2004) Hypertophic osteopathy secondary to gastric squamous cell carcinoma in a horse. ''Equine Vet Educ'', 16:304-307. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref> Diagnosis is made by exclusion of other causes of weight loss and gastroscopy. | ||
| + | |||
| + | ==Treatment and Prognosis== | ||
| + | In most cases, surgical resection is not possible<ref>East, L.M, Savage, C.J (1998) Abdominal neoplasia (excluding urogenital tract). ''Vet Clin North Am Equine Pract'', 14:475-493. In: Zimmel, D.N (2010) ''Neoplasia of the Alimentary Tract'' in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 15.</ref> and the prognosis is grave. | ||
| + | |||
| + | ==References== | ||
| + | <references/> | ||
Revision as of 18:13, 10 August 2010
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This article is still under construction. |
| Also known as: | Gastric Neoplasia |
| See also: | Colic, Gastric Causes |
Description
Squamous cell carcinoma is the most common tumor of the equine stomach.[1]. It can affect the cardia and upper squamous regions of the stomach, resulting in a persistent mild colic, commonly seen soon after feeding. The tumor can invade and metastasize to lymph nodes, the lungs and regions palpable on rectal examination.[1]
Clinical Signs and Diagnosis
The main clinical signs include weight loss and general ill health.(Merck) Hypertrophic osteopathy associated with this neoplastic disease has been reported in one horse.[2] Diagnosis is made by exclusion of other causes of weight loss and gastroscopy.
Treatment and Prognosis
In most cases, surgical resection is not possible[3] and the prognosis is grave.
References
- ↑ 1.0 1.1 Olsen, S.N (1992) Squamous-cell carcinoma of the equine stomach: a report of 5 cases. Vet Rec, 131:170-173. In: Zimmel, D.N (2010) Neoplasia of the Alimentary Tract in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) Equine Internal Medicine (Third Edition), Saunders, Chapter 15.
- ↑ Schleining, J.A, Voss, E.D (2004) Hypertophic osteopathy secondary to gastric squamous cell carcinoma in a horse. Equine Vet Educ, 16:304-307. In: Zimmel, D.N (2010) Neoplasia of the Alimentary Tract in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) Equine Internal Medicine (Third Edition), Saunders, Chapter 15.
- ↑ East, L.M, Savage, C.J (1998) Abdominal neoplasia (excluding urogenital tract). Vet Clin North Am Equine Pract, 14:475-493. In: Zimmel, D.N (2010) Neoplasia of the Alimentary Tract in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) Equine Internal Medicine (Third Edition), Saunders, Chapter 15.