Difference between revisions of "Category:Primary Innate Immunity Deficiencies"

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*Recurrent bacterial infection
 
*Recurrent bacterial infection
 
*Neutrophilia ([[Neutrophils|neutrophils]] remain in the blood and are unable to fight infection in the tissue)
 
*Neutrophilia ([[Neutrophils|neutrophils]] remain in the blood and are unable to fight infection in the tissue)
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[[Category:Primary Innate Immunity Deficiencies]]
  
 
====Bovine Leukocyte Adhesion Deficiency (BLAD)====
 
====Bovine Leukocyte Adhesion Deficiency (BLAD)====
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*Missence mutation of -Asp-128-Gly in CD18 molecule
 
*Missence mutation of -Asp-128-Gly in CD18 molecule
 
*Recurrent infection, e.g. pneumonia
 
*Recurrent infection, e.g. pneumonia
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[[Category:Primary Innate Immunity Deficiencies]]
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[[Category:Primary Immunodeficiency]]
 
[[Category:Primary Immunodeficiency]]

Revision as of 13:47, 12 August 2010

Deficiencies of Innate Immunity

Canine Cyclic Haematopoiesis

Canine Leukocyte Adhesion Deficiency (CLAD)

  • Occurs in Irish Setters
  • Missence mutation of -Cys-36-Ser- in CD18 molecule
    • CD18 is required for neutrophil migration and phagocytosis
  • Recurrent bacterial infection
  • Neutrophilia (neutrophils remain in the blood and are unable to fight infection in the tissue)

Bovine Leukocyte Adhesion Deficiency (BLAD)

  • Occurs in Holstein cattle
  • Missence mutation of -Asp-128-Gly in CD18 molecule
  • Recurrent infection, e.g. pneumonia

Pages in category "Primary Innate Immunity Deficiencies"

The following 3 pages are in this category, out of 3 total.