Difference between revisions of "Cholangitis"
Jump to navigation
Jump to search
(→Causes) |
|||
| Line 4: | Line 4: | ||
==Signalment== | ==Signalment== | ||
Cholangitis is common in cats, where a periportal hepatocellular necrosis is seen together with | Cholangitis is common in cats, where a periportal hepatocellular necrosis is seen together with | ||
| − | the presence of neutrophils in the portal area. Cats can be acutely or | + | the presence of neutrophils in the portal area. Cats can be acutely or chronically affected, and |
| − | male, pure bred cats are | + | male, pure bred cats are over represented. |
The condition is also seen in calves as a secondary condition to bacterial infection, such as Salmonella. | The condition is also seen in calves as a secondary condition to bacterial infection, such as Salmonella. | ||
Revision as of 18:17, 1 November 2010
Introduction
Cholangitis describes an inflammation of the biliary tract. Cholangiohepatitis describes the inflammation of the biliary tract and the surrounding hepatic parenchyma. It is typically categorised into Neutrophilic Cholangitis and Lymphocytic Cholangitis.
Signalment
Cholangitis is common in cats, where a periportal hepatocellular necrosis is seen together with the presence of neutrophils in the portal area. Cats can be acutely or chronically affected, and male, pure bred cats are over represented.
The condition is also seen in calves as a secondary condition to bacterial infection, such as Salmonella.
Causes
- ascending infections from the intestine where stasis of bile flow has developed
- associated with organisms excreted via the bile such as salmonellosis infection in calves
Laboratory Findings
Raised ALT and serum bilirubin levels.
Histology
Lymphocytic infiltration of the portal areas is seen, with mild fibrosis and biliary hyperplasia.